Title:
HIGH PERMEABILITY COMPOSITION AND APPLICATION THEREOF
Document Type and Number:
Japanese Patent JP2015205912
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To develop a novel compound which can be delivered effectively and efficiently to a site of action in a certain state (e.g., disease) for preventing, reducing, or treating the state in a biological subject while minimizing side effects.SOLUTION: The invention provides a composition or a pharmaceutical composition of a novel high permeability composition (HPC) of a parent compound which can pass through a biological barrier with a high permeability efficiency. The HPC can be converted into a parent drug or a compound related to the parent drug, (e.g., metabolite) after passing through one or more biological barriers, and thereby can provide treatment under the condition that the parent drug or the compound related to the parent drug can treat.
Inventors:
YU CHONGXI
Application Number:
JP2015144217A
Publication Date:
November 19, 2015
Filing Date:
July 21, 2015
Export Citation:
Assignee:
YU CHONGXI
International Classes:
A61K31/18; A61K31/164; A61K31/165; A61K31/192; A61K31/198; A61K31/22; A61K31/221; A61K31/223; A61K31/232; A61K31/24; A61K31/40; A61K31/404; A61K31/405; A61K31/407; A61K31/415; A61K31/426; A61K31/43; A61K31/4453; A61K31/4462; A61K31/4465; A61K31/454; A61K31/47; A61K31/5375; A61K31/5415; A61K31/545; A61K31/55; A61K31/557; A61K31/5575; A61K31/565; A61K31/57; A61K31/616; A61K31/64; A61K38/00; A61K38/22; A61P1/16; A61P1/18; A61P3/10; A61P5/16; A61P9/00; A61P9/12; A61P11/00; A61P11/14; A61P15/18; A61P17/00; A61P17/10; A61P17/14; A61P17/16; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P27/00; A61P27/06; A61P27/12; A61P35/00; A61P37/06; A61P43/00; C07C219/06; C07C219/10; C07C219/14; C07C229/36; C07C229/42; C07C229/58; C07C233/47; C07C233/54; C07C233/83; C07C237/04; C07C311/41; C07C403/12; C07C403/20; C07C405/00
Foreign References:
| WO2008029200A1 | 2008-03-13 | |||
| WO2008007171A1 | 2008-01-17 | |||
| WO2008093173A1 | 2008-08-07 | |||
| WO2008020270A1 | 2008-02-21 |
Other References:
JPN6014005909; ＨＯＶＧＡＡＲＤ，Ｌ． ｅｔ ａｌ: Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１２， Ｎｏ．３, 1995, ｐ．３８７-３９２
JPN6016021218; Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１３， Ｎｏ．１０, 1996, ｐ．１５２４-１５２９
JPN6014005911; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
JPN6016021218; Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｒｅｓｅａｒｃｈ Ｖｏｌ．１３， Ｎｏ．１０, 1996, ｐ．１５２４-１５２９
JPN6014005911; 小田切 優樹 他: 'プロドラッグ' 新・ドラッグデリバリーシステム , 20000131, ｐ．１２３-１３５, 株式会社シーエムシー
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Shimura
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Shimura
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