Title:
麻酔を誘発する方法
Document Type and Number:
Japanese Patent JP6916542
Kind Code:
B2
Abstract:
The present invention provides methods for determining the selectivity of an anesthetic for an anesthetic-sensitive receptor by determining the molar water solubility of the anesthetic. The invention further provides methods for modulating the selectivity of an anesthetic for an anesthetic-sensitive receptor by altering or modifying the anesthetic to have higher or lower water solubility. The invention further provides methods of inducing anesthesia in a subject by administering an effective amount of an anesthetic compound identified according to the present methods.
Inventors:
Robert Jay Brosnan
Application Number:
JP2019160900A
Publication Date:
August 11, 2021
Filing Date:
September 04, 2019
Export Citation:
Assignee:
The Regents of the University of California
International Classes:
A61K31/01; A61K31/045; A61K31/015; A61K31/02; A61K31/025; A61K31/05; A61K31/08; A61K31/13; A61K31/341; A61K31/351; A61K31/357; A61K31/4174; A61K31/4748; A61K31/5513; A61P23/00; A61P25/20; A61P43/00
Other References:
Anesthesia and Analgesia,1999年,Vol.88,p.867-876
Attorney, Agent or Firm:
Michiko Matsutani
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro