Title:
親水性薬物を経皮吸収させる方法
Document Type and Number:
Japanese Patent JP6865239
Kind Code:
B2
Abstract:
To provide a method for percutaneous absorption of a hydrophilic drug by using a low molecular gelling agent in order to improve not only a use feeling but also percutaneous absorption properties.SOLUTION: A method for percutaneous absorption of a hydrophilic drug is characterized by using a lipid peptide compound consisting of at least one of a compound represented by the formula (1) and an analogous compound thereof or a pharmaceutically usable salt thereof (in the formula, R1 represents an aliphatic group having 9 to 23 carbon atoms, R2 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms which may have a branched chain having 1 or 2 carbon atoms, R3 represents a -(CH2)n-X group, n represents a numeral number of 1 to 4, and X represents an amino group, a guanidino group, a -CONH2 group, or a fused heterocycle comprising a 5- or 6-membered ring or 5- and 6-membered rings which may have 1 to 3 nitrogen atoms).SELECTED DRAWING: None
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Inventors:
Masahiro Goto
Imoto Takayuki
Takehisa Iwama
Nobuhide Miyaji
Imoto Takayuki
Takehisa Iwama
Nobuhide Miyaji
Application Number:
JP2019031758A
Publication Date:
April 28, 2021
Filing Date:
February 25, 2019
Export Citation:
Assignee:
Kyushu University
Nissan Chemical Co., Ltd.
Nissan Chemical Co., Ltd.
International Classes:
A61K8/64; A61K9/06; A61K9/107; A61K47/06; A61K47/14; A61K47/18; A61K47/44; A61P17/00; A61Q19/00
Foreign References:
| WO2011052613A1 | ||||
| WO2012096276A1 |
Attorney, Agent or Firm:
Hanabusa Patent and Trademark Office