Title:
HUMAN 7-TRANSMEMBRANE TYPE RECEPTOR
Document Type and Number:
Japanese Patent JPH10179178
Kind Code:
A
Abstract:
To obtain the subject receptor having a preserved 7-times transmembrane residue and useful for the treatment of infectious diseases such as infectious diseases caused by HIV-1 and HIV-2, a pain, a cancer, an anorexia, a limosis, an asthma, a Parkinsonian disease, an acute cardiac failure, etc.
This 7-times transmembrane receptor is a polypeptide having at least 70% homology with an amino acid sequence of the formula, and called as human 7-times transmembrane type receptor 'HBMBU14'. The receptor is obtained by culturing a host cell transformed by a vector containing an isolated nucleic acid molecule encoding the above polypeptide capable of being expressed by a human cDNA contained in ATCC deposit number 98226.
Inventors:
ELSHOURBAGY NABAL A
BERGSMA DERK J
ELLIS CATHERINE E
BERGSMA DERK J
ELLIS CATHERINE E
Application Number:
JP30140297A
Publication Date:
July 07, 1998
Filing Date:
September 25, 1997
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORP
International Classes:
A61K38/00; A61K39/395; A61K48/00; A61P1/04; A61P9/00; A61P9/10; A61P19/10; A61P25/00; A61P25/28; A61P31/12; A61P35/00; A61P37/08; C07K14/705; C07K14/715; C07K16/28; C12N5/00; C12N15/09; C12N5/10; C12N15/00; C12N15/12; C12P21/02; C12Q1/68; C12R1/91; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61K48/00; C07K14/705; C07K16/28; C12N5/10; C12Q1/68
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)
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