HUMAN EPIDERMAL KERATINIZED CELL ACTIVATOR

Japanese Patent JP3825069

B2

PURPOSE: To obtain the subject activator capable of shortening the culture time in a culture system of human epidermal keratinized cells, thus leading to increase in the passage number of cultured cells, or useful for treating burns, wounds etc., containing, as active ingredient, an oligosaccharide alginate (salt). CONSTITUTION: This activator contains, as active ingredient, an oligosaccharide alginate or a salt thereof. The active ingredient is obtained by subjecting an alginic acid lyase produced by Alteromonas microbes to alginic acid (salt) to carry out a treatment. It is preferable that the oligosaccharide alginate (salt) be ≤1000 in molecular weight and the disaccharide to pentasaccharide constituent thereof account for 80-10wt.% of the whole active ingredient.

JP3974167	Methods and compositions for the treatment of genetic, tumor and viral infections, and for the prevention of programmed cell death (apoptosis).
WO/1995/013701	NOVEL FAS PROTEIN AND METHODS OF USE THEREOF

Takahara Hidenari
Hiura Nozomi
Tomoaki Oguri
Eiji Yamamoto

JP17959895A

September 20, 2006

June 23, 1995

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Maruha Co., Ltd.

A61K31/70; C12N9/88; A01N1/02; A61K8/00; A61K8/73; A61K31/7016; A61K31/702; A61L27/00; A61P17/00; A61P17/02; A61Q19/00; C07H3/04; C07H3/06; C12N5/00; C12N5/07; C12N5/071; C12P19/04; C12R1/01; (IPC1-7): A61K31/70; A01N1/02; A61K7/48; C07H3/04; C07H3/06; C12N5/06; C12N9/88; C12P19/04; //A61L27/00; (C12N9/88; C12R1:01); (C12P19/04; C12R1:01)

JP3015475A
JP3273002A
JP4169188A

Yusuke Hiraki
Ishii Teiji

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