HUMAN HEMATOPOIETIC STEM CELL AND PROGENITOR CELL ANTIGEN AND METHODS FOR ITS USE

Title:

HUMAN HEMATOPOIETIC STEM CELL AND PROGENITOR CELL ANTIGEN AND METHODS FOR ITS USE

Document Type and Number:

Japanese Patent JP2006246898

Kind Code:

A

Abstract:

To provide an antigen expressed by a hematopoietic stem cell and a progenitor cell, a method of especially using such antigens for cell separation and cell purification, and a novel polypeptide.

Disclosed is an isolated polypeptide, wherein the polypeptide comprises amino acid sequences comprising an extracellular N-terminus represented by SEQ ID No. 2: aa 20-107; a first transmembrane region: aa 107-126; a first cytoplasmic loop: aa 127-157; a second transmembrane region: aa 158-179; a first extracellular loop: aa 180-435; a third transmembrane region: aa 436-454; a second cytoplasmic loop: aa 455-480; a forth transmembrane region: aa 481-503; a second extracellular loop: aa 504-792; a fifth transmembrane region: aa 793-816; or a cytoplasmic C-terminus aa 817-865.

Inventors:

MIRAGLIA SHERI
GODFRY WAYNE G
YIN AMY
BUCK DAVID

Application Number:

JP2006153522A

Publication Date:

September 21, 2006

Filing Date:

June 01, 2006

Export Citation:

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Assignee:

AMCELL CORP

International Classes:

C12N15/02; C12N15/09; A61K35/14; A61K35/28; A61K35/407; A61K35/44; A61L27/00; A61P7/00; A61P35/00; A61P35/02; C07K14/47; C07K14/705; C07K16/18; C07K16/28; C07K16/40; C12N5/06; C12N5/08; C12N5/10; C12N5/20; C12N15/12; C12P21/08; G01N33/53; G01N33/569; G01N33/577

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura

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