Title:
白血球付着分子 VLA-4に対するヒト化抗体
Document Type and Number:
Japanese Patent JP4115517
Kind Code:
B2
Abstract:
The invention provides humanized immunoglobulins that specifically bind to the VLA-4 ligand, and methods of treatment using the same. The methods are particularly useful for the treatment of multiple sclerosis.
Inventors:
Beding, Mary M.
Léger, Olivier Jay.
Jose, Saldanha
Jones, Thalane Es.
Léger, Olivier Jay.
Jose, Saldanha
Jones, Thalane Es.
Application Number:
JP51977095A
Publication Date:
July 09, 2008
Filing Date:
January 25, 1995
Export Citation:
Assignee:
Elan Pharmaceuticals, Inc.
International Classes:
C12N15/09; G01N33/53; A61K39/395; A61P7/00; A61P29/00; A61P37/00; C07H21/04; C07K16/18; C07K16/28; C07K16/46; C12N5/00; C12N5/10; C12N15/13; C12P21/08; A61K38/00; C12R1/91; C07K
Domestic Patent References:
| JP2006045237A | ||||
| JP4502408A |
Foreign References:
| WO1993015764A1 |
Other References:
Agents Actions, 1993, Vol.39 (Special Confernece Issue), p.C177-C179
Protein Engineering, 1991, Vol.4, No.7, p.773-783
Protein Engineering, 1993, Vol.6, No.8, p.971-980
Protein Engineering, 1991, Vol.4, No.7, p.773-783
Protein Engineering, 1993, Vol.6, No.8, p.971-980
Attorney, Agent or Firm:
Takeshi Oshio
Takashi Ishida
Takashi Ishida