Title:
HYPOTENSIVE COMPOSITION
Document Type and Number:
Japanese Patent JPS54157840
Kind Code:
A
Abstract:
A material and composition for reducing blood pressure are provided. The blood pressure in animals is reduced by administering lergotrile, viz. 2-chloro-6-methylergoline-8 beta -acetonitrile or pharmaceutically acceptable salts thereof either alone or in combination with a substance which is known to reduce blood pressure. A composition is provided comprising a unit dosage form of lergotrile and a substance which is known to reduce blood pressure. For lergotrile, any of its physiologically- and pharmacologically-active metabolites in the body can be substituted.
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Inventors:
JIYON DEII FUAANSUTOROMU
ARAN EFU SUBEDO
ARAN EFU SUBEDO
Application Number:
JP4983379A
Publication Date:
December 13, 1979
Filing Date:
April 24, 1979
Export Citation:
Assignee:
MASSACHUSETTS INST TECHNOLOGY
International Classes:
C07D457/04; A61K31/475; A61K31/48; A61P9/12; (IPC1-7): A61K31/48