Title:
【発明の名称】GnRHに対する免疫応答を刺激し、哺乳動物を免疫的に生殖不能化するための剤及び方法
Document Type and Number:
Japanese Patent JP2703574
Kind Code:
B2
Abstract:
A method for suppressing the reproduction capacity of a mammal by stimulating the immune system thereof in order to raise antibodies which bind to the natural GnRH of the mammal comprises using a stimulating agent which is obtained by conjugating
a) a GnRH molecule in which one or more of the ten naturally occurring amino acids is replaced by another amino acid with a more reactive side chain to
b) an immunostimulant carrier molecule.
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Inventors:
Debited Double Silver Size
Bruce Day Murphy
Ruben The Ray Maple Toft
Bikram Mithra
Anne Francis Allen
Bruce Day Murphy
Ruben The Ray Maple Toft
Bikram Mithra
Anne Francis Allen
Application Number:
JP24263688A
Publication Date:
January 26, 1998
Filing Date:
September 29, 1988
Export Citation:
Assignee:
The University of Saskatchewan
International Classes:
A61K38/24; A61K39/00; A61K39/385; A61K39/39; A61K38/04; A61K47/42; A61K47/48; A61P13/02; A61P15/00; (IPC1-7): A61K39/385; A61K38/24; A61K39/00; A61K47/42
Other References:
【文献】欧州公開181236(EP,A1)
Attorney, Agent or Firm:
Heiyoshi Odashima