Title:
【発明の名称】修飾された末端を有するアミノ酸及びペプチド
Document Type and Number:
Japanese Patent JPH08505854
Kind Code:
A
Abstract:
Compounds which have one of structural formulae (I) or (II). AA is an amino acid residue or an amino acid chain of two or more amino acid residues, excluding the N-terminal and the C-terminal from said amino acid residue or amino acid chain of two or more amino acid residues; R1 is hydrogen or an alkyl group having from 1 to 8 carbon atoms; R2 is selected from the group consisting of (i) a substituted or unsubstituted hydrocarbon having from 1 to 20 carbon atoms, and (ii) (a). R4 is an aliphatic hydrocarbon having 1 to 4 carbon atoms. R4 may be substituted or unsubstituted. R3 is selected from the group consisting of (i) hydrogen; (ii) (b), wherein R5 is hydrogen or a nitro group; and (iii) (c), wherein each of R6, R7, and R8 is hydrogen or methyl. The above compounds are useful as pharmaceuticals for inhibiting the growth of target cells, viruses, or virally-infected cells.
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Inventors:
Carrie. Prasad
Application Number:
JP51627994A
Publication Date:
June 25, 1996
Filing Date:
January 11, 1994
Export Citation:
Assignee:
Magainin Pharmaceuticals, Inc.
International Classes:
A61K38/00; A61K31/16; A61K31/165; A61P31/00; A61P31/04; A61P31/12; A61P33/00; C07C237/20; C07C237/22; C07C279/10; C07C279/12; C07C279/14; C07C279/18; C07C279/34; C07C279/36; C07K5/023; C07K5/027; C07K5/065; C07K5/068; C07K5/083; C07K5/09; C07K5/093; C07K5/11; (IPC1-7): C07K5/068; A61K31/16; A61K31/165; A61K38/00; C07C237/22; C07C279/10; C07C279/12; C07C279/18; C07C279/34; C07K5/023; C07K5/027; C07K5/065; C07K5/083; C07K5/09; C07K5/093; C07K5/11
Attorney, Agent or Firm:
Shimizu Hatsushi