【発明の名称】スクアレンシンテターゼ及びプロテインファルネシルトランスフェラーゼのインヒビターとしてのシクロブタン誘導体

Japanese Patent JPH08505646

A

The present invention provides a compound of formula (I) processes for the preparation of the compounds of the invention in addition to intermediates useful in these processes, a pharmaceutical composition, and a method of treating disorders resulting from an excess of cholesterol or cancer or a fungal infection.

Baker, William Earl
Lockway, Todd Double
Donor, Bee Gregory
Cien, Wan
Rosenberg, Saul H
Huatku Howley, Stephen A
O'Connor, Stephen Jei
Stout, David M
Juan, Anthony K. El
Garby, David S
Prasad, Raj Yunan Dan
The Sullivan, The Gerard M

JP51325595A

June 18, 1996

October 20, 1994

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Abbot Laboratories

A61K31/195; A61K31/215; A61K31/34; A61K31/341; A61K31/357; A61K31/36; A61K31/38; A61K31/381; A61K31/40; A61K31/41; A61K31/42; A61K31/421; A61K31/4245; A61K31/44; A61K31/4409; A61K31/4418; A61P3/06; A61P7/00; A61P9/10; A61P31/04; A61P43/00; C07C69/52; C07C69/74; C07C231/02; C07C233/19; C07C233/58; C07C233/59; C07C233/60; C07C233/61; C07C233/62; C07C233/63; C07C235/36; C07C235/40; C07C237/24; C07C245/14; C12N9/99; C07C251/42; C07C259/08; C07C275/26; C07C311/51; C07C323/40; C07C323/46; C07C327/20; C07C327/36; C07C327/38; C07D207/325; C07D213/40; C07D257/04; C07D257/06; C07D263/24; C07D271/06; C07D271/10; C07D277/20; C07D277/34; C07D285/16; C07D285/18; C07D307/42; C07D307/52; C07D309/32; C07D317/60; C07D319/06; C07D333/08; C07D333/58; (IPC1-7): C07C233/60; A61K31/34; A61K31/40; C07C69/52; C07C69/74; C07C231/02; C07C251/42; C07C275/26; C07C323/40; C07C327/20; C07C327/36; C07C327/38; C07D207/325; C07D307/42; C07D307/52; C07D333/08; C12N9/99

Yoshio Kawaguchi (2 outside)

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