Title:
【発明の名称】TNFとPDE―IVのインヒビターとしてのキノリンカルボキサミド
Document Type and Number:
Japanese Patent JP2000510865
Kind Code:
A
Abstract:
The subject invention concerns novel compounds of the general formula (i) that are useful in treating disease states, such as those states associated with proteins that mediate cellular activity. The compounds of the subject invention can be used, for example, to inhibit tumor necrosis factor and/or phosphodiesterase IV, The subject invention also concerns methods for treating disease states using the compounds of the invention.
Inventors:
Dyke, Hazel Joan
John Gary, Montana
Rowe, Christopher
Kendall, Hana Jane
Sabin, Balati Margaret
John Gary, Montana
Rowe, Christopher
Kendall, Hana Jane
Sabin, Balati Margaret
Application Number:
JP54178897A
Publication Date:
August 22, 2000
Filing Date:
May 20, 1997
Export Citation:
Assignee:
DARWIN DISCOVERY LIMITED
International Classes:
C07D215/26; A61K31/00; A61K31/47; A61K31/472; A61K31/4725; A61K45/06; A61P43/00; C07D215/48; C07D401/12; C07D401/14; C07D417/12; (IPC1-7): C07D215/48; A61P43/00; A61K31/4725; C07D401/12; C07D401/14; C07D417/12
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)