Title:
【発明の名称】細胞増殖阻害剤および細胞分化の段階を判定する分子マーカーとしての、グアニル酸結合タンパク質(GBP-1)
Document Type and Number:
Japanese Patent JP2002523104
Kind Code:
A
Abstract:
The present invention provides an eukaryotic expression vector comprising the Guanylate Binding Protein 1 (GBP-1) gene or parts thereof. The introduction of said vector comprising said gene or parts thereof into cells can be used to induce phenotypical changes of said cells and can, thus, be used for modulation of cell differentiation. Additionally, the present invention provides said vector for the treatment of cancer, sarcoma, lymphoma, hemangioma, artherosclerosis or restenosis, but also the treatment of inflammatory diseases like chronic ulcerative diseases, psoriasis, insect bites, freezing or burning injuries, wound healing or Morbus Crohn.
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Inventors:
Sturtul, Michael
Cornari, Emanuele
Cornari, Emanuele
Application Number:
JP2000567723A
Publication Date:
July 30, 2002
Filing Date:
August 23, 1999
Export Citation:
Assignee:
Bavarian Nordic Research Institute Actieslskab
International Classes:
G01N33/53; A61K31/7105; A61K31/711; A61K38/00; A61K39/395; A61K39/42; A61K45/00; A61K48/00; A61P17/00; A61P29/00; A61P35/00; A61P37/02; C07K14/16; C07K14/47; C07K16/18; C07K19/00; C12N5/10; C12N7/00; C12N15/09; C12N15/12; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/566; A61K39/00; (IPC1-7): C12N15/09; A61K31/7105; A61K31/711; A61K38/00; A61K39/395; A61K39/42; A61K45/00; A61K48/00; A61P17/00; A61P29/00; A61P35/00; A61P37/02; C07K14/16; C07K14/47; C07K16/18; C07K19/00; C12N5/10; C12N7/00; C12P21/02; C12Q1/02; C12Q1/68; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Takehiko Suzue (4 outside)