Title:
【発明の名称】CD2/LFA-3相互作用の阻害剤を用いる抗原提示細胞による皮膚障害の予防または治療の方法
Document Type and Number:
Japanese Patent JPH07502496
Kind Code:
A
Abstract:
Methods of using inhibitors of the CD2/LFA-3 interaction in treating skin conditions characterized by increased T cell activation and abnormal antigen presentation in the dermis and epidermis in mammals, including humans. Such conditions include psoriasis, UV damage, atopic dermatitis, cutaneous T cell lymphoma such as mycosis fungoides, allergic and irritant contact dermatitis, lichen planus, alopecia areata, pyoderma gangrenosum, vitiligo, ocular cicatricial pemphigoid, and urticaria.
Inventors:
Wolner, Barbarapee.
Cooper, Kevin Dee.
Cooper, Kevin Dee.
Application Number:
JP50724893A
Publication Date:
March 16, 1995
Filing Date:
October 06, 1992
Export Citation:
Assignee:
Byogen incorporated
The Regents of the University of Michigan
The Regents of the University of Michigan
International Classes:
A61K31/519; A61K38/17; A61K39/02; A61K39/395; A61K47/48; A61K38/00; A61P17/00; A61P17/02; A61P17/06; A61P17/14; A61P17/16; A61P27/02; A61P35/00; A61P37/00; A61P37/08; C07K14/705; C07K16/28; C12N5/10; C12N15/02; C12P21/08; A61K; (IPC1-7): A61K39/395; A61K38/00; A61K39/395; C12N5/10; C12N15/02; C12P21/08
Attorney, Agent or Firm:
Hidekazu Miyoshi (1 outside)