Title:
【発明の名称】静脈内適用のためのIgM製剤の製造方法
Document Type and Number:
Japanese Patent JP2001504092
Kind Code:
A
Abstract:
An IgM-containing immunoglobulin solution is treated with a protease in a method for producing an immunoglobulin solution that is adequate for intravenous administration and having an Igm proportion higher than 5 weight % with respect to the immunoglobulin proportion. The iv-tolerant preparation obtained is characterized by not being chemically modified and by having low anticomplementary ACA activity.
Inventors:
Renchu, Marx
Application Number:
JP51787598A
Publication Date:
March 27, 2001
Filing Date:
October 14, 1997
Export Citation:
Assignee:
Rotkretz Stiftung Zentral Laboratorium Brutz Pendienst S.R.K.
International Classes:
A61K39/395; A61P31/00; C07K16/06; A61K38/00; G01N33/68; C12S3/00; (IPC1-7): A61K39/395; A61K38/00; C07K16/06
Attorney, Agent or Firm:
Tadashi Hagino (4 outside)