Title:
【発明の名称】レニン阻害剤
Document Type and Number:
Japanese Patent JPH06500111
Kind Code:
A
Abstract:
A renin inhibiting compound of formula (I), wherein X is O, NH or S and G is a mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof; with the proviso that the compound is not N-(3-(4-Morpholino)propyl)-5(S)-(2(S)-(1(S)-(4-(methoxymethoxy)piperid in-1-yl)carbonyl-2-phenyl)ethoxyhexanamido)-6-cyclohexyl-4(S)-hydroxy- 2(S)-isopropylhexanamide.
Inventors:
Baker, William Earl
Boyd, Stephen A
Juan, Anthony K.L.
Stein, Herman H
Denitsen, Jiyoung F
Hatchins, Challes D'Abri
Rosenberg, Soul H
Boyd, Stephen A
Juan, Anthony K.L.
Stein, Herman H
Denitsen, Jiyoung F
Hatchins, Challes D'Abri
Rosenberg, Soul H
Application Number:
JP51507691A
Publication Date:
January 06, 1994
Filing Date:
August 02, 1991
Export Citation:
Assignee:
Abbot Laboratories
International Classes:
A61K31/445; A61K31/4427; A61K31/495; A61K31/505; A61K31/535; A61K31/54; A61P9/12; A61P43/00; C07D211/46; C07D401/12; C07D405/12; C07D413/12; C07D417/12; C07D451/06; C07D451/14; (IPC1-7): C07D211/46; A61K31/445; A61K31/495; A61K31/505; A61K31/535; A61K31/54; C07D401/12; C07D413/12; C07D417/12
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)