Title:
低温保存システムのためのアイスシーディング装置
Document Type and Number:
Japanese Patent JP4693834
Kind Code:
B2
Abstract:
An apparatus for ice seeding during cryopreservation of biological samples such as cells, harvested tissues, and cellular biological constructs such as culture tissue equivalents wherein ice seeding is performed by discharging a liquefied or chilled gas (60) from a nozzle (21) to the surface of a container (40) containing said biological sample in cryopreservative. Inside a freezing chamber (70), containers (40) are placed on racks (30) that are located proximal to a sprayrail (20) containing nozzles (21). Ice seeding is performed by discharge of liquefied or chilled gas (60) from the nozzles to the container surface at the solid-liquid equilibrium temperature of the cryopreservative. Localized cooling of the container surface by the discharge results in ice seed formation within the container (40).
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Inventors:
Maury Di Cosman
Application Number:
JP2007314892A
Publication Date:
June 01, 2011
Filing Date:
December 05, 2007
Export Citation:
Assignee:
ORGANOGENESIS INC.
International Classes:
C12M1/00; G01N33/48; A01N1/02; C12M1/38; C12N1/04; F25D3/10; F25D17/04; F25D25/00; F25D29/00; G01N1/42
Domestic Patent References:
| JP61255655A | ||||
| JP1150775A |
Foreign References:
| US4739625 | ||||
| WO1996001882A1 |
Attorney, Agent or Firm:
Aoyama Aoi
Yasuo Shibata
Samejima Mutsumi
Yasuo Shibata
Samejima Mutsumi