PURPOSE: To effectively immobilize the subject substance at the low cost, by adsorbing peptide or protein, and a polymer having a crosslinkable functional group, onto a fine porous film surface, and crosslinking the polymer to form a polymer network in which these materials are contained.
CONSTITUTION: Peptide or protein (for example; bovine cardiac myoglobulin or the like), and a polymer having a crosslinkable functional group (for example; polyethyleneimine or the like), are adsorbed onto a surface of a flat microporous membrane (for example; polyvinylidene difluoride film or the like), and then the polymer is treated by a crosslinking agent (for example; 1,4-phenylene diisothiocyanate or the like) to form a crosslinkage, whereby a polymer network including peptide or protein inside, is produced, and peptide or protein can be effectively immobilized on an insoluble base.
| WO/2004/007069 | MEMBRANE, DEVICE AND METHOD FOR REMOVING PROTEASES FROM LIQUIDS |
| WO/2018/189142 | EXTRACORPOREAL BLOOD CIRCUIT |
JIEIMUZU EMU KUURU
FUUBAATO KESUTAA
