Title:
血液凝固第ＸＩＩＩ因子の阻害剤
Document Type and Number:
Japanese Patent JP2021522200
Kind Code:
A
Abstract:
本発明は、血液凝固第ＸＩＩＩ因子の新規阻害剤としての一般式（Ｉ）の化合物、その合成の方法、および、血液凝固第ＸＩＩＩ因子に関連する疾患の予防または治療のためのその使用に関する。【化１】【選択図】図４Ｂ
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Inventors:
Pastanack Ralph
Hills martin
Viewholt christian
Hills martin
Viewholt christian
Application Number:
JP2020557961A
Publication Date:
August 30, 2021
Filing Date:
April 17, 2019
Export Citation:
Assignee:
Zedira Game Behr
International Classes:
C07K7/06; A61K38/08; A61P7/00; A61P7/02; A61P9/10; A61P13/12; A61P17/00; A61P17/06; A61P17/10; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/12; A61P29/00; A61P31/10; A61P43/00
Foreign References:
| WO2008055488A1 | 2008-05-15 | |||
| WO2014012858A1 | 2014-01-23 | |||
| WO2014090835A1 | 2014-06-19 |
Other References:
HEIL, A. ET AL.: "Differences in the inhibition of coagulation factor XIII-A from animal species revealed by Michael a", THROMBOSIS RESEARCH, vol. １３１（５）, JPN7023001054, 2013, pages 214 - 222, ISSN: 0005016948
VAN DER WILDT, B. ET AL.: "Strategies towards in vivo imaging of active transglutaminase type 2 using positron emission tomogra", AMINO ACIDS, vol. ４９（３）, JPN7023001052, 2017, pages 585 - 595, ISSN: 0005016949
VAN DER WILDT, B. ET AL.: "Strategies towards in vivo imaging of active transglutaminase type 2 using positron emission tomogra", AMINO ACIDS, vol. ４９（３）, JPN7023001052, 2017, pages 585 - 595, ISSN: 0005016949
Attorney, Agent or Firm:
Nagoya International Patent Service Corporation