Title:
胆汁酸誘導体、特に、オベチコール酸の合成のための中間体
Document Type and Number:
Japanese Patent JP7034093
Kind Code:
B2
Abstract:
The invention relates to compounds of general formula (I):wherein: , R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease.
Inventors:
Alexander Charles Waymouth-Wilson
Zophia Comsta
Laura Wallis
Timothy Evans
Yeuan Davis
Carl Otter
Reese Bachelor
Zophia Comsta
Laura Wallis
Timothy Evans
Yeuan Davis
Carl Otter
Reese Bachelor
Application Number:
JP2018560597A
Publication Date:
March 11, 2022
Filing Date:
May 18, 2017
Export Citation:
Assignee:
NP UK Limited
International Classes:
C07J71/00; A61K31/575; A61K31/58; A61P1/16; C07J9/00; C07J41/00; C07J43/00
Foreign References:
| WO2007080951A1 | ||||
| WO2016079517A1 | ||||
| WO2016079518A1 | ||||
| WO2016079519A1 | ||||
| WO2016079520A1 |
Other References:
Biosci. Biotechnol. Biochem.,68,2004年,1332-1337
J. Org. Chem.,2002年,67,6764-6771
Chemistry and Physics of Lipids,2001年,109,135-143
J. Org. Chem.,2002年,67,6764-6771
Chemistry and Physics of Lipids,2001年,109,135-143
Attorney, Agent or Firm:
Toru Ishikawa