Title:
ステロイド４，６－ジエンの６，７－α－エポキシ化のための方法及び中間体
Document Type and Number:
Japanese Patent JP7034094
Kind Code:
B2
Abstract:
The invention relates to a process for preparing a compound of general formula (Ia): wherein R2, Y, R4 and R5 are as defined herein, wherein the epoxidation is conducted using an oxidant and methyltrioxorhenium as a catalyst (MeReO3). The invention also relates to certain compounds per se. The compounds are intermediates in the synthesis of synthetic bile acids.
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Inventors:
Alexander Charles Waymouth-Wilson
Zophia Comsta
Laura Wallis
Timothy Evans
Zophia Comsta
Laura Wallis
Timothy Evans
Application Number:
JP2018560672A
Publication Date:
March 11, 2022
Filing Date:
May 18, 2017
Export Citation:
Assignee:
NP UK Limited
International Classes:
C07J71/00; C07J9/00; C07J41/00; C07J43/00
Other References:
Biosci. Biotechnol. Biochem.,2004年,68,1332-1337
Tetrahedron,1997年,53,8129-8136
J. Org. Chem.,2002年,67,6764-6771
Chemistry and Physics of Lipids,2001年,109,135-143
Eur. J. Org. Chem.,2001年,3731-3739
Tetrahedron: Asymmetry,1999年,10,3977-3989
Tetrahedron,1997年,53,8129-8136
J. Org. Chem.,2002年,67,6764-6771
Chemistry and Physics of Lipids,2001年,109,135-143
Eur. J. Org. Chem.,2001年,3731-3739
Tetrahedron: Asymmetry,1999年,10,3977-3989
Attorney, Agent or Firm:
Toru Ishikawa