コレステロール管理および関連使用のためのケトン化合物および組成物

Japanese Patent JP2007525408

A

The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising a ketone compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

Gene-Louis Dashu
Carmen Daniella Onishi

JP2005513788A

September 06, 2007

December 24, 2003

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Esperion Therapeutics, Incorporated

C07C49/17; A61K31/122; A61K31/131; A61K31/185; A61K31/191; A61K31/20; A61K31/225; A61K31/275; A61K31/337; A61K31/341; A61K31/351; A61K31/41; A61K31/4166; A61K31/42; A61K31/4365; A61K31/6615; A61K31/664; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P9/10; A61P9/12; A61P13/12; A61P15/10; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P43/00; C07C49/185; C07C49/215; C07C49/245; C07C49/258; C07C49/507; C07C49/723; C07C49/743; C07C49/747; C07C49/784; C07C49/82; C07C49/83; C07C49/86; C07C50/30; C07C59/347; C07C59/82; C07C59/84; C07C59/90; C07C62/18; C07C62/22; C07C69/716; C07C69/738; C07C69/757; C07C235/74; C07C261/04; C07C309/07; C07C309/24; C07D233/72; C07D233/74; C07D233/84; C07D233/86; C07D257/04; C07D261/12; C07D305/12; C07D307/33; C07D309/12; C07D309/30; C07D309/40; C07D495/04; C07D519/00; C07F9/09; C07F9/24; C07F9/44

Yoshinobu Murofushi

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