PURPOSE: To provide a manipulator system for operation easy to sterilize the necessary place of a master manipulator and also easy to perform emergency sterilization treatment.

CONSTITUTION: In a manipulator system for operation equipped with a master manipulator set within a region capable of being operated by an operator, a slave manipulator set so as to access to an operating field and moving so as to follow the operation of the master manipulator and the treatment appliance held to the slave manipulator and inserted in the body cavity, the master manipulator is constituted so as to be capable of being divided into at least a handle part 16 operated by an operator and an arm part 17. Therefore, the handle part of the master manipulator is easily introduced into a sterilizing device.