Title:
ポサコナゾール中間体の製造
Document Type and Number:
Japanese Patent JP2013532131
Kind Code:
A
Abstract:
The present invention relates to process for the preparation of a chiral compound of formula (IX) or a salt thereof, wherein Y1 and Y2 are independently F or Cl, preferably F, the crystalline compound of formula (IX) as such, and its use for the preparation of an antifungal agent.
Inventors:
De Sorza, Dominique
Jyoshi, Silly Lang Buoy
Booter, satin
Pise, Avinai Sea
Jayabang, Datsutatraya N
Metcal, Shashikant Day
Jyoshi, Silly Lang Buoy
Booter, satin
Pise, Avinai Sea
Jayabang, Datsutatraya N
Metcal, Shashikant Day
Application Number:
JP2013510613A
Publication Date:
August 15, 2013
Filing Date:
May 18, 2011
Export Citation:
Assignee:
SANDOZ AKTIENGESELLSCHAFT
International Classes:
C07D405/06; A61K31/4196; A61K31/496; A61P31/10; C07D307/12; C07D405/14; C12P7/62; C07B61/00; C07C17/361; C07C25/24
Domestic Patent References:
| JPH10502637A | 1998-03-10 |
Foreign References:
| WO1994025452A1 | 1994-11-10 | |||
| WO1996033178A1 | 1996-10-24 | |||
| US5349099A | 1994-09-20 | |||
| WO2009141837A2 | 2009-11-26 | |||
| EP1394162A1 | 2004-03-03 | |||
| WO1997022710A1 | 1997-06-26 | |||
| WO2009058267A2 | 2009-05-07 | |||
| WO2008136279A1 | 2008-11-13 | |||
| WO1996038443A1 | 1996-12-05 |
Other References:
JPN6015007573; Ｓａｋｓｅｎａ， Ａｎｉｌ Ｋ．； Ｇｉｒｉｊａｖａｌｌａｂｈａｎ， Ｖｉｙｙｏｏｒ Ｍ．； Ｌｏｖｅｙ， Ｒａｙｍｏｎｄ Ｇ．； Ｐｉｋｅ， Ｒｕｓｓｅｌｌ Ｅ．； Ｗａｎｇ， Ｈａｉｙａｎ； Ｇａ: 'Ｈｉｇｈｌｙ ｓｔｅｒｅｏｓｅｌｅｃｔｉｖｅ ａｃｃｅｓｓ ｔｏ ｎｏｖｅｌ ２，２，４-ｔｒｉｓｕｂｓｔｉｔｕｔｅｄ ｔｅｔｒａｈｙｄｒｏｆｕｒａｎｓ ｂｙ ｈａｌｏｃｙｃｌｉｚａｔｉｏｎ： ｐ' Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ ３６（１１）, 1995, １７８７-９０
JPN6015007574; Ｋｏｎｏｓｕ， Ｔｏｓｈｉｙｕｋｉ； Ｔａｊｉｍａ， Ｙａｗａｒａ； Ｍｉｙａｏｋａ， Ｔａｋｅｏ； Ｏｉｄａ， Ｓａｄａｏ: 'Ｃｏｎｃｉｓｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｏｐｔｉｃａｌｌｙ ａｃｔｉｖｅ ｏｘｉｒａｎｅ ｐｒｅｃｕｒｓｏｒｓ ｆｏｒ ｔｈｅ ｐｒｅｐａｒａｔｉｏｎ ｏｆ ｔｒｉａｚｏｌｅ ａｎｔｉｆｕｎｇａｌ' Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ ３２（５１）, 1991, ７５４５-４８
JPN6014047536; 社団法人日本化学会: 化学便覧応用化学編第６版 , 20030130, 第１７８頁, 丸善株式会社
JPN6015007574; Ｋｏｎｏｓｕ， Ｔｏｓｈｉｙｕｋｉ； Ｔａｊｉｍａ， Ｙａｗａｒａ； Ｍｉｙａｏｋａ， Ｔａｋｅｏ； Ｏｉｄａ， Ｓａｄａｏ: 'Ｃｏｎｃｉｓｅ ｓｙｎｔｈｅｓｉｓ ｏｆ ｏｐｔｉｃａｌｌｙ ａｃｔｉｖｅ ｏｘｉｒａｎｅ ｐｒｅｃｕｒｓｏｒｓ ｆｏｒ ｔｈｅ ｐｒｅｐａｒａｔｉｏｎ ｏｆ ｔｒｉａｚｏｌｅ ａｎｔｉｆｕｎｇａｌ' Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ ３２（５１）, 1991, ７５４５-４８
JPN6014047536; 社団法人日本化学会: 化学便覧応用化学編第６版 , 20030130, 第１７８頁, 丸善株式会社
Attorney, Agent or Firm:
Kawaguchi International Patent Office