Title:
MANUFACTURE OF (+)S-2-HYDROXY-2-METHYL-HEXANOIC ACID
Document Type and Number:
Japanese Patent JPS61238757
Kind Code:
A
Abstract:
A method for preparing an important stereospecific intermediate in the synthesis of prostaglandin analogs is disclosed. Said intermediate is (+)S-2-hydroxy-2-methyl-hexanoic acid and is prepared via an asymmetric halolactonization reaction utilizing L-proline as the chiral agent.
Inventors:
POORU FUREDERITSUKU KOOREI
Application Number:
JP8443686A
Publication Date:
October 24, 1986
Filing Date:
April 14, 1986
Export Citation:
Assignee:
MILES LAB
International Classes:
C07B31/00; C07B53/00; C07C51/00; C07C51/06; C07C51/09; C07C59/01; C07C67/00; C07C405/00; C07D207/16; C07D498/04; (IPC1-7): B01J27/06; C07B53/00; C07C51/06; C07C59/01; C07D498/04
Domestic Patent References:
| JPS53108922A | 1978-09-22 |
Attorney, Agent or Firm:
Heiyoshi Odashima