Title:
MELANIN SUPPRESSING AGENT
Document Type and Number:
Japanese Patent JP3105691
Kind Code:
B2
Abstract:
PURPOSE: To obtain a melanin suppressing agent capable of preventing and improving melanization by acting on an epidermal melanin metabolism system and having excellent effect capable of preventing and improving stain or ephelis due to suntan, etc., and excellent in blending property to a cosmetic base.
CONSTITUTION: This melanin suppressing agent contains an amine derivative of formula I (R1 is 4-40C straight-chain, branched chain or cyclic saturated or unsaturated hydrocarbon group; R2 to R6 are H or 1-10C hydrocarbon groups whose hydrogen atoms may be substituted with one or more OH groups) or its acid addition salt, e.g. 1-(2-hydroxyethylamino)-3-tetradesiloxy-2-propanol. The compound is blended in an amount of 0.0001-10wt.%, especially 0.001-2wt.% based on total composition of a cosmetic to provide a beautifying cosmetic excellent in effect capable of preventing and treating melanization. The compound of formula 1 is obtained by adding an amine derivative of formula 3 to a glycidyl ether derivative of formula 2.
Inventors:
Yukihiro Yada
Mitsutoshi Kimura
Kazuhiko Higuchi
Genji Imokawa
Yukihiro Ohashi
Taketoshi Fujimori
Akira Kawamata
Mitsutoshi Kimura
Kazuhiko Higuchi
Genji Imokawa
Yukihiro Ohashi
Taketoshi Fujimori
Akira Kawamata
Application Number:
JP6420793A
Publication Date:
November 06, 2000
Filing Date:
March 23, 1993
Export Citation:
Assignee:
Kao Corporation
International Classes:
A61K8/30; A61K8/00; A61K8/41; A61K31/13; A61K31/133; A61K31/138; A61P17/00; A61P43/00; A61Q19/00; A61Q19/02; C07C217/28; C07C217/30; (IPC1-7): A61K7/48; A61K7/00; A61K31/133; A61K31/138; A61P17/00; A61P43/00
Other References:
【文献】特許2711783(JP,B2)
Attorney, Agent or Firm:
Miyuki Ariga (3 outside)