Metallic coating nano crystalline silicon as a base of active surface reinforcement Raman spectroscopic analysis (SERS)

Title:

Metallic coating nano crystalline silicon as a base of active surface reinforcement Raman spectroscopic analysis (SERS)

Document Type and Number:

Japanese Patent JP6029614

Kind Code:

B2

Abstract:

The methods, systems 400 and apparatus disclosed herein concern metal 150 impregnated porous substrates 110, 210. Certain embodiments of the invention concern methods for producing metal-coated porous silicon substrates 110, 210 that exhibit greatly improved uniformity and depth of penetration of metal 150 deposition. The increased uniformity and depth allow improved and more reproducible Raman detection of analytes. In exemplary embodiments of the invention, the methods may comprise oxidation of porous silicon 110, immersion in a metal salt solution 130, drying and thermal decomposition of the metal salt 140 to form a metal deposit 150. In other exemplary embodiments of the invention, the methods may comprise microfluidic impregnation of porous silicon substrates 210 with one or more metal salt solutions 130. Other embodiments of the invention concern apparatus and/or systems 400 for Raman detection of analytes, comprising metal-coated porous silicon substrates 110, 210 prepared by the disclosed methods.

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Inventors:

Chan Serena
Berlin Andrew
Kwon Sung Hoon
Sandara Rajan Narayan
Yamakawa Mineo

Application Number:

JP2014096540A

Publication Date:

November 24, 2016

Filing Date:

May 08, 2014

Export Citation:

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Assignee:

INTEL CORPORATION

International Classes:

G01N21/65; B01D67/00; B01D71/02; B82Y5/00; B82Y15/00; B82Y40/00; C12Q1/68; G01J3/44

Domestic Patent References:

JP627056A

Foreign References:

WO2002095070A2

Other References:

Vo-Dinh T, TrAC, Trends in Analytical Chemistry,英国,1998年 9月,Vol.17 Issues 8-9, P557-582

Attorney, Agent or Firm:

Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto

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