Title:
METHOD, COMPOSITION AND LIBRARY RELATING TO PNA DIMER AND PNA OLIGOMER SYNTHESIS
Document Type and Number:
Japanese Patent JP2010279375
Kind Code:
A
Abstract:
To provide a method, composition and library relating to a PNA dimer and PNA oligomer.
The invention relates to a field of PNA dimers and PNA oligomers. It discloses a solid support composition. The solid support composition is (a) an acid-forming cleavable linker and (b) a PNA dimer including a base labile N-terminal protecting group bound to the solid support by the cleavable linker in a cleavable manner wherein the loading of the PNA dimer on the solid support is ≥0.08 mmol per one gram.
Inventors:
CASALE RALPH A
COULL JAMES M
DEY SUBHAKAR
GAN KEVIN Z
KOWALCZYK BRUCE A
COULL JAMES M
DEY SUBHAKAR
GAN KEVIN Z
KOWALCZYK BRUCE A
Application Number:
JP2010165394A
Publication Date:
December 16, 2010
Filing Date:
July 22, 2010
Export Citation:
Assignee:
APPLIED BIOSYSTEMS LLC
International Classes:
C12N15/09; C07H21/00; C07K1/00; C07K1/04; C07K2/00; C07K9/00; C07K14/00; C07K17/02; C08G63/48; C08G63/91; C12Q1/68; C40B40/06; C40B40/10; C40B50/14; C07K
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita