Title:
METHOD AND COMPOSITION FOR TREATMENT AND MANAGEMENT OF CANCER AND OTHER DISEASES BY USING IMMUNOMODULATORY COMPOUND
Document Type and Number:
Japanese Patent JP2013126999
Kind Code:
A
Abstract:
To provide a method for treatment and prevention of specific type cancers, such as primary and metastatic cancers, and cancers unresponsive or resistant to conventional chemotherapy.
There is disclosed a medicine for treatment or prevention of multiple myeloma, which contains a therapeutically or prophylactically effective amount of a compound represented by formula 1: 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione or its pharmaceutically acceptable salt, solvate, or stereoisomer.
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Inventors:
ZELDIS JEROME B
Application Number:
JP2013038222A
Publication Date:
June 27, 2013
Filing Date:
February 28, 2013
Export Citation:
Assignee:
CELGENE CORP
International Classes:
A61K31/454; A61K45/00; A61K9/20; A61K9/48; A61K31/00; A61K31/198; A61K31/40; A61K31/4035; A61K31/425; A61K31/445; A61K31/515; A61K31/573; A61K35/12; A61K35/14; A61K35/28; A61K38/00; A61K38/21; A61K38/22; A61K45/06; A61K51/00; A61P1/04; A61P1/16; A61P3/06; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P9/04; A61P9/10; A61P9/14; A61P11/00; A61P11/06; A61P11/16; A61P17/00; A61P17/02; A61P17/06; A61P17/10; A61P17/12; A61P19/02; A61P19/08; A61P19/10; A61P25/00; A61P27/02; A61P27/06; A61P27/10; A61P27/14; A61P29/00; A61P31/00; A61P31/04; A61P31/08; A61P31/10; A61P31/12; A61P31/18; A61P31/22; A61P33/00; A61P33/02; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P41/00; A61P43/00; C07D209/46; C07D401/04; C07J5/00
Other References:
JPN6008036228; ＨＩＤＥＳＨＩＭＡ， Ｔ． ｅｔ ａｌ．: Ｂｌｏｏｄ Ｖｏｌ．９６， Ｎｏ．９, 2000, ｐｐ．２９４３-２９５０
JPN6013028069; Ｊ Ｉｍｍｕｎｏｌ ｖｏｌ．１６３， ｎｏ．１, 1999, ｐ．３８０-６
JPN6013028071; Ｂｉｏｏｒｇ Ｍｅｄ Ｃｈｅｍ Ｌｅｔｔ ｖｏｌ．９， ｎｏ．１１, 1999, ｐ．１６２５-３０
JPN6010028486; Ｓｅｍｉｎａｒｓ ｉｎ Ｏｎｃｏｌｏｇｙ Ｖｏｌ．２８，Ｎｏ．６, 2001, Ｐ．５９７-６０１
JPN6010028487; Ｃａｎｃｅｒ Ｒｅｓｅａｒｃｈ Ｖｏｌ．６２, 200204, Ｐ．２３００-２３０５
JPN6013028069; Ｊ Ｉｍｍｕｎｏｌ ｖｏｌ．１６３， ｎｏ．１, 1999, ｐ．３８０-６
JPN6013028071; Ｂｉｏｏｒｇ Ｍｅｄ Ｃｈｅｍ Ｌｅｔｔ ｖｏｌ．９， ｎｏ．１１, 1999, ｐ．１６２５-３０
JPN6010028486; Ｓｅｍｉｎａｒｓ ｉｎ Ｏｎｃｏｌｏｇｙ Ｖｏｌ．２８，Ｎｏ．６, 2001, Ｐ．５９７-６０１
JPN6010028487; Ｃａｎｃｅｒ Ｒｅｓｅａｒｃｈ Ｖｏｌ．６２, 200204, Ｐ．２３００-２３０５
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Mami Hino
Yoshimitsu Maki
Yasuhito Suzuki
Norio Omori
Mami Hino
Yoshimitsu Maki
Yasuhito Suzuki