To provide a method for determining presence or absence of medullary thyroid cancer, which can specifically detect medullary thyroid cancer.
A method for determining presence or absence of medullary thyroid cancer uses a method having a process (a) for detecting expression of a splicing variant of CEACAM4 gene such as a cDNA composed of a specific base sequence in a sample for determination or the splicing variant such as a protein composed of an amino acid sequence encoded by the base sequence, etc., and a process (b) for evaluating that possibility of a sample donor for determination having medullary thyroid cancer is high when the expression of the splicing variant of CEACAM4 gene or a protein encoded by the splicing variant is detected in the process (a).
MOCHIZUKI TORU
HATAKEYAMA KEIICHI
YAMAGUCHI KEN
WO2003095622A2 | 2003-11-20 |
JPN6017000608; database GenBank , 20080724, AK298701
JPN6017000609; 日本内科学会雑誌 vol.86 no.7, 1997, pp.94-100
Seiji Ozawa
Yusaku Tokai
Makoto Horiuchi
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