To more sensitively measure an antigen which appears in the blood of patients suffering from cancers by performing immunoassay utilizing an antigen-antibody reaction between an antigen and the antibody to the antigen.
An antigen-antibody reaction is caused between an antigen adhering to the surfaces of bloods cell and the antibody to the antigen. The antibody can be a monoclonal antibody or polyclonal antibody. In addition, an antibody solution to the antigen can be used for the reaction after the solution is absorbed to the blood cell of a healthy man so as to suppress a nonspecific reaction. The immunoassay can be performed by various method. In one preferable mode, the agglutination of blood cells is measured. Namely, blood cells are crosslinked and agglutinated by causing a reaction between an antigen adhering to the surfaces of the blood cells and the antibody to the antigen and the antigen adhering to the surfaces of blood cells is measured by measuring the agglutination of the blood cells.
HIYAMUTA SHUICHI
IRIE SHINJI
KADOTA AKIHIKO
