Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR PRODUCING CYCLOPROPYLAMIDE COMPOUND
Document Type and Number:
Japanese Patent JP2009132621
Kind Code:
A
Abstract:

To provide a method for efficiently producing 3-amino-2-hydroxyhexanoic acid cyclopropylamide, suitable for industrial production, to provide an intermediate compound useful for the production method, and to provide a method for producing the intermediate compound.

This method for producing the 3-amino-2-hydroxyhexanoic acid cyclopropylamide includes reacting 3-propyloxiranecarboxylic acid cyclopropylamide with a metal azide to obtain 3-amino-2-hydroxyhexanoic acid cyclopropylamide, and then reducing the compound to obtain the 3-amino-2-hydroxyhexanoic acid cyclopropylamide. The 3-propyloxiranecarboxylic acid cyclopropylamide can be produced by reacting 3-propyloxiranecarboxylic acid with cyclopropylamine. An optically active 3-amino-2-hydroxyhexanoic acid cyclopropylamide can be produced using, as a starting material, optically active (2S, 3R)-3-propyloxiranecarboxylic acid which can be produced by a diastereomer method.


Inventors:
ONISHI TOMOYUKI
TORII TAKAYOSHI
Application Number:
JP2006067342A
Publication Date:
June 18, 2009
Filing Date:
March 13, 2006
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
AJINOMOTO KK
International Classes:
C07C231/12; C07C237/04; C07C247/12; C07D301/32; C07D303/48; C07D491/22; C07B53/00; C07B57/00; C07B61/00