Title:
鏡像異性的に純粋なα-置換カルボン酸の製造方法
Document Type and Number:
Japanese Patent JP4261799
Kind Code:
B2
Abstract:
In accordance with the present invention there are provided methods for producing enantiomerically pure ±-substituted carboxylic acids, such as, for example, ±-amino acids and ±-hydroxy acids, said method comprising an aldehyde or ketone with a cyanide and ammonia or an ammonium salt or an amine, in the presence of a nitrilase or a polypeptide having nitrilase activity which stereoselectively hydrolyzes the amino nitrile or cyanohydrin intermediate under conditions sufficient to produce the carboxylic acid.
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Inventors:
Madden, Mark
Weiner, David, Paul
Chaplin, jennifer, anne
Robertson, Dan
Weiner, David, Paul
Chaplin, jennifer, anne
Robertson, Dan
Application Number:
JP2001548688A
Publication Date:
April 30, 2009
Filing Date:
December 29, 2000
Export Citation:
Assignee:
Verenium Corporation
International Classes:
C07C229/36; C12N15/09; C12N9/78; C12P7/42; C12P13/04; C12P13/06; C12P13/22; C12P41/00
Domestic Patent References:
| JP8131188A | ||||
| JP6237789A | ||||
| JP4099495A | ||||
| JP1317392A | ||||
| JP4079894A | ||||
| JP63500004A |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ishii Teiji
Satoshi Fujita
Ishii Teiji