Title:
ハロピリジル-アザシクロペンタン誘導体及びその中間体の合成方法
Document Type and Number:
Japanese Patent JP4364313
Kind Code:
B2
Abstract:
The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.
Inventors:
Node Manabu
Nakamura Daisaku
Satoo Fujiwara
Shogo Ichihashi
Nakamura Daisaku
Satoo Fujiwara
Shogo Ichihashi
Application Number:
JP54337599A
Publication Date:
November 18, 2009
Filing Date:
September 03, 1998
Export Citation:
Assignee:
Nihon Medi-Physics Co., Ltd.
International Classes:
C07D487/08; C07D487/04
Other References:
PAVRI, N. P. et al., A NEW [4 + 2] CYCLOADDITION STRATEGY FOR THE SYNTHESIS OF N-ACYL-7-AZABICYCLO[2.2.1]HEPTAN-2-ONES: A FORMAL SYNTHESIS OF (±)-EPIBATIDINE, Tetrahedron Letters , 1997年, Vol. 38, No. 46 , pp.7993-7996
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio