Title:
C-MET二量体化及び活性化を阻害するための方法と組成物
Document Type and Number:
Japanese Patent JP2008507252
Kind Code:
A
Abstract:
The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.
Inventors:
Wick Ramachege, Dyneerie.
Kong-Bertrand, Monica
Kong-Bertrand, Monica
Application Number:
JP2006544006A
Publication Date:
March 13, 2008
Filing Date:
December 10, 2004
Export Citation:
Assignee:
GENENTECH,INC.
International Classes:
C12N15/09; A61K38/00; A61K38/03; A61K38/08; A61K38/17; A61K38/18; A61K39/395; A61K45/00; A61K48/00; A61P1/04; A61P1/16; A61P3/10; A61P5/00; A61P5/14; A61P7/04; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/08; A61P43/00; C07K14/475; C07K16/18; C07K16/22; C07K16/28; C07K16/32; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/15; G01N33/50; G01N33/68; C12P21/08
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori