METHODS FOR PRODUCING 1,2,3,4-TETRAHYDRO-4-OXO-3-QUINOLINECARBOXYLATE COMPOUND AND 2,3-DIHYDRO-4(1H)-QUINOLINONE COMPOUND

Title:

METHODS FOR PRODUCING 1,2,3,4-TETRAHYDRO-4-OXO-3-QUINOLINECARBOXYLATE COMPOUND AND 2,3-DIHYDRO-4(1H)-QUINOLINONE COMPOUND

Document Type and Number:

Japanese Patent JP2006083079

Kind Code:

A

Abstract:

To provide methods for highly purely and profitably producing a 2,3-dihydro-4(1H)-quinolinone compound and a 1,2,3,4-tetrahydro-4-oxo-3-quinolinecarboxylate compound as its precursor, respectively.

This method for profitably producing a 2,3-dihydro-4(1H)-quinolinone compound represented by formula (4) (R1 is H or a 1 to 4C alkyl which may be branched) is characterized by condensation-cycling an anthranilate derivative in the presence of an alkali metal alkoxide and a water-immiscible organic solvent to obtain the 1,2,3,4-tetrahydro-4-oxo-3-quinolinecarboxylate compound, and then reacting the compound in the presence of an alkaline aqueous solution without isolating the compound.

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Inventors:

YAMADA MASAHIRO
MAEHARA AKIRA
KAWAI YOSHIHISA

Application Number:

JP2004267746A

Publication Date:

March 30, 2006

Filing Date:

September 15, 2004

Export Citation:

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Assignee:

TAOKA CHEMICAL CO LTD

International Classes:

C07D215/22; C07D215/56

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