Title:
c-kit/SCF/pAKTの状態を測定するための方法及び定量アッセイ
Document Type and Number:
Japanese Patent JP4204974
Kind Code:
B2
Abstract:
The present invention relates to a method for predicting the response to administration of a chemotherapeutic or biological therapeutic agent consisting of tyrosine kinase inhibitors to an individual, comprising detecting the amount of one or a plurality of biological markers in a tissue or cell sample originating from the individual, wherein the biological markers are cellular components to the c-kit pathway and comparing the amount of the one or the plurality of biological markers detected in subpart (a) with the amount detected in one or a plurality of control tissue or cell samples, wherein a response to the administration of a chemotherapeutic or biological therapeutic agent to an individual is predicted based on the comparison of the amount of the one or the plurality of biological markers from one or a plurality of control tissue or cell samples.
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Inventors:
Bacchus, Sarah S.
Application Number:
JP2003521325A
Publication Date:
January 07, 2009
Filing Date:
August 21, 2002
Export Citation:
Assignee:
Ventana Medical Systems Incorporated
International Classes:
G01N33/574; A61K31/00; C12N5/08; C12Q1/02; G01N33/15; G01N33/48; G01N33/50; G01N33/53
Domestic Patent References:
| JP2000515964A |
Foreign References:
| WO1999053953A1 | ||||
| WO1999041613A1 |
Attorney, Agent or Firm:
Hidekazu Miyoshi