Title:
16α-メチルまたはエチル置換エストロゲン
Document Type and Number:
Japanese Patent JP2004505093
Kind Code:
A
Abstract:
The invention makes a 16α-substituted steroidal compound available having formula 1, wherein the dotted ring is a fully saturated, a fully aromatic or a saturated ring with a Δ5-10 double bond; R1 is (C1-C3)alkyl or (C2-C3)alkenyl, and each of these groups can be substituted with one or more halogens; R2 is (C1-C4;)alkyl, (C2-C4)alkenyl or methylene, and each of these groups can be substituted with one or more halogens; R3 is methyl or ethyl; or a prodrug thereof, which compound can be used for an estrogen receptor α selective treatment
Inventors:
Mestress, jjorday
Rosen, Heubert Jan Josef
Huenemann, Herrit Helmann
Rosen, Heubert Jan Josef
Huenemann, Herrit Helmann
Application Number:
JP2002515917A
Publication Date:
February 19, 2004
Filing Date:
July 23, 2001
Export Citation:
Assignee:
Akzo Novel N B
International Classes:
A61K31/565; A61P5/30; A61P15/18; A61P43/00; C07J1/00; C07J51/00; A61K31/569; C07J71/00; (IPC1-7): C07J1/00; A61K31/569; A61P5/30; A61P15/18; A61P43/00
Attorney, Agent or Firm:
Yoshio Kawaguchi
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuru Inoue
Akio Ichiiri
Makoto Ono
Katsuma Osaki