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Title:
チオラーゼ、HMG−CoA合成酵素及びHMG−CoA還元酵素活性を有するポリペプチドをコードしている遺伝子を使用するメバロン酸、イソプレン、及びイソプレノイドの生産
Document Type and Number:
Japanese Patent JP2014519811
Kind Code:
A
Abstract:
The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in microorganisms via the heterologous expression of the mvaE and mvaS genes from the organisms Listeria grayi DSM 20601, Enterococcus faecium, Enterococcus gallinarum EG2, and Enterococcus casseliflavus.

Inventors:
Beck, the Zucker Lee cue
A mirror, Michael See
Pelles, Caroline M
A プライ mark, ユリヤ Ey
Pucci, Jeff Py
Verres, Derek h
Application Number:
JP2014508154A
Publication Date:
August 21, 2014
Filing Date:
April 27, 2012
Export Citation:
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Assignee:
ダニスコ you S ink
The Goodyear Tire & Rubber company
International Classes:
C12N1/21; C12N1/15; C12N1/19; C12P5/02; C12N15/09
Domestic Patent References:
JP2009538601A2009-11-12
JP2009207376A2009-09-17
Other References:
"acetyl-CoA acetyltransferase [Listeria grayi DSM 20601]", NCBI, [ONLINE], ACCESSION NO.EFI85313, 29-JUN-2010, vol. [検索日:2016年4月15日], JPN6016015020, ISSN: 0003302688
"hydroxymethylglutaryl-CoA synthase [Listeria grayi DSM 20601]", NCBI, [ONLINE], ACCESSION NO.EFI85314, 29-JUN-2010, vol. [検索日:2016年4月15日], JPN6016015021, ISSN: 0003302689
COMPREHENSIVE NATURAL PRODUCTS II, CHEMISTRY AND BIOLOGY, 2010, PP.493-516, JPN6016015022, ISSN: 0003302690
Attorney, Agent or Firm:
Yukuzo Yamazaki
Toshiaki Akamatsu
尾首 亘聰
Masako Okutani
Tadao Naito
Imai 千裕
Yoshiko Takeyama