Title:
モキシデクチンを含むマイクロ粒子およびその製造方法
Document Type and Number:
Japanese Patent JP7040818
Kind Code:
B2
Abstract:
The present invention relates to microparticles comprising moxidectin and a biodegradable polymer, wherein the microparticles comprising moxidectin have a shape allowing a moxidectin drug to be uniformly distributed in spherical biodegradable polymer particles, and the average particle diameter of the microparticles is 80-130 µm. The present invention relates to: extended release microparticles capable of continuously maintaining a heartworm disease prevention effect for 3 months to 6 months by administering microparticles comprising moxidectin; and a preparation method therefor. In addition, the present invention is prepared such that the average diameters of the particles have a predetermined micrometer size, and thus reduces a foreign body sensation and pain during administration into an animal through injection, thereby enabling administration through injection to be facilitated.
Inventors:
Kim Ju-hee
Application Number:
JP2020533631A
Publication Date:
March 23, 2022
Filing Date:
September 05, 2018
Export Citation:
Assignee:
INVENTAGE LAB INC.
International Classes:
A61K9/50; A61K31/438; A61K47/34; A61P33/10
Domestic Patent References:
| JP2009155302A | ||||
| JP2007099760A | ||||
| JP2014237713A | ||||
| JP2008150596A | ||||
| JP2005118619A | ||||
| JP11279054A | ||||
| JP8034732A | ||||
| JP2013535489A | ||||
| JP2010531303A | ||||
| JP2009504778A | ||||
| JP2002506797A |
Foreign References:
| WO2017045966A1 | ||||
| WO2017009219A1 | ||||
| WO2016118494A1 | ||||
| CN102211008A | ||||
| KR1020060005472A |
Other References:
Advanced Drug Delivery Reviews,2004年,Vol.56,p.1453-1466
Attorney, Agent or Firm:
Katsumi Iseki
Shuhei Kaneko
Wataru Onishi
Shuhei Kaneko
Wataru Onishi