Title:
有糸分裂キネシン阻害剤
Document Type and Number:
Japanese Patent JP2007530545
Kind Code:
A
Abstract:
The present invention relates to N-substituted benzylic aniline derivatives that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Inventors:
Robert M, Garbatchiyo
Olson, Christie M
Edward S. Tusbar
Torrent, marisel
Olson, Christie M
Edward S. Tusbar
Torrent, marisel
Application Number:
JP2007505031A
Publication Date:
November 01, 2007
Filing Date:
March 18, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07C215/16; A61K31/136; A61K31/165; A61K31/198; A61K31/216; A61K31/415; A61K31/42; A61K31/445; A61K31/495; A61P1/04; A61P19/02; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00; C07C211/00; C07C211/48; C07C211/53; C07C215/20; C07C215/24; C07C215/50; C07C229/18; C07C229/30; C07C237/06; C07C237/10; C07C237/12; C07D211/26; C07D231/12; C07D261/08; C07D295/04; C07D295/12; C12N9/99
Domestic Patent References:
| JP2005526091A | 2005-09-02 | |||
| JP2005515208A | 2005-05-26 | |||
| JP2003048881A | 2003-02-21 | |||
| JP2002525348A | 2002-08-13 | |||
| JPS6490158A | 1989-04-06 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura