MUSCLE CELL AND THEIR USE IN CARDIAC REPAIR

Title:

MUSCLE CELL AND THEIR USE IN CARDIAC REPAIR

Document Type and Number:

Japanese Patent JP2011219494

Kind Code:

A

Abstract:

To deal with the limitations of the present heart transplantation methodologies existing in the therapy for heart diseases.

Muscle cells and methods for using the muscle cells are provided. In one embodiment, transplantable skeletal muscle cell compositions and the methods of use thereof are provided. In one embodiment, the muscle cells can be transplanted into subjects having disorders characterized by insufficient cardiac function, e.g. congestive heart failure, by administering the skeletal myoblasts to the subjects. The muscle cells can be autologous, allogeneic, or xenogeneic to the recipient. Furthermore, modification, masking or removal of antigens existing on the surface of the cells in the compositions to inhibit the lysis of the cells, when administering the compositions to the subjects are proposed.

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Inventors:

EDGE ALBERT

Application Number:

JP2011152353A

Publication Date:

November 04, 2011

Filing Date:

July 08, 2011

Export Citation:

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Assignee:

MYTOGEN INC

International Classes:

A61K35/12; C12N15/09; A61K35/34; A61K39/395; A61K48/00; A61L27/00; A61P9/10; A61P43/00; C12N5/077; C12N5/10

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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