新規フェニルアラニン誘導体

Japanese Patent JP4895067

B2

Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof have an antagonistic effect on the alpha 4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which alpha 4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sj¦gren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.

Suzuki Shiniku
Toshihiko Yoshimura
Hiroyuki Izawa
Kazuyuki Sagi
Makino Shingo
Eiji Nakanishi
Murata Masahiro
Naoshi Tsuji

JP2002532416A

March 14, 2012

September 28, 2001

Click for automatic bibliography generation  

AJINOMOTO CO.,LTD.

C07D209/46; A61K31/395; A61K31/4015; A61K31/403; A61K31/4035; A61K31/407; A61K31/41; A61K31/435; A61K31/4355; A61K31/4365; A61K31/437; A61K31/438; A61K31/4412; A61K31/4439; A61K31/45; A61K31/472; A61K31/48; A61K31/4985; A61K31/55; A61P1/00; A61P1/04; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P35/04; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D207/38; C07D207/452; C07D209/48; C07D209/52; C07D209/66; C07D209/76; C07D211/88; C07D217/24; C07D217/26; C07D221/14; C07D221/20; C07D223/10; C07D223/18; C07D401/12; C07D403/12; C07D471/04; C07D487/04; C07D495/04; C07D207/44

WO1999064395A1	1999-12-16
WO2001012183A1	2001-02-22
WO1999010312A1	1999-03-04
WO1999036393A1	1999-07-22

Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Takaki Nishijima
Atsushi Hakoda

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