Title:
ニトロオキシシクロアルカン誘導体
Document Type and Number:
Japanese Patent JP2012509875
Kind Code:
A
Abstract:
A compound having the structure wherein Y is selected from the group consisting of -C(O)OR2, -C(O)NHR8, -C(CH2)1-2OR3, OH, and or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
Inventors:
Ali, Am Jiyad
Baker, Robert Kay
Ruprecht, Kathleen M
Law, Michael Man-Chu
Whitehead, Brent
Baker, Robert Kay
Ruprecht, Kathleen M
Law, Michael Man-Chu
Whitehead, Brent
Application Number:
JP2011537443A
Publication Date:
April 26, 2012
Filing Date:
July 27, 2009
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07C203/08; A61K31/19; A61K31/198; A61K31/21; A61K31/41; A61K31/4196; A61K45/00; A61P9/12; A61P43/00; C07C219/12; C07C235/40; C07C311/51; C07D249/08; C07D257/04
Domestic Patent References:
| JP2011529892A | 2011-12-15 |
Foreign References:
| US20050065194A1 | 2005-03-24 | |||
| US20020183366A1 | 2002-12-05 |
Other References:
JPN6013062503; Ｂｒｕｆａｎｉ， Ｍａｒｉｏ ｅｔ ａｌ．: 'Ｓｙｎｔｈｅｓｉｓ ｏｆ ｓｏｍｅ ｍｙｏ-ｉｎｏｓｉｔｏｌ ｎｉｔｒａｔｅｓ' Ｃａｒｂｏｈｙｄｒａｔｅ Ｒｅｓｅａｒｃｈ ２１８, 1991, ２２９-２３２
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama