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Title:
薬物を保持した非水系組成物およびその製造方法
Document Type and Number:
Japanese Patent JP7149611
Kind Code:
B2
Abstract:
An object of the present invention is to provide a non-aqueous composition having a drug carried therein, the composition being capable of preparing a drug-containing fat emulsion that is usable as an injection, an eye drop, a nasal drop, an inhalant, or the like by being mixed with an aqueous medium in use without producing a drug-containing fat emulsion in advance, and a method for producing the non-aqueous composition. The non-aqueous composition having a drug carried therein of the present invention as a resolution for achieving the object is characterized by comprising an oil or fat, a slightly water soluble drug, and an emulsifier which are dissolved in a polyhydric alcohol as a water soluble carrier at a content of the oil or fat of 0.05 to 250 mg/g, a weight ratio of the slightly water soluble drug to the oil or fat (slightly water soluble drug/(oil or fat)) of 0.0001 to 50 (provided that the total content of the slightly water soluble drug and the oil or fat is at most 300 mg/g), and a content of the emulsifier of 20 to 500 mg/g.

Inventors:
Kiichiro Nabeta
Application Number:
JP2019509437A
Publication Date:
October 07, 2022
Filing Date:
March 31, 2018
Export Citation:
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Assignee:
Techno Guard Co., Ltd.
International Classes:
A61K47/44; A61K9/08; A61K47/10; A61K47/14; A61K47/24
Domestic Patent References:
JP2013536805A
JP2010270023A
JP2013209347A
JP4164024A
JP10504291A
JP2013525485A
Attorney, Agent or Firm:
Yukifumi Tsujita
Shimizu Yoshihiro
Shinichi Abe