Title:
ＳＬＣ３０Ａ８変異を含む非ヒト動物および使用方法
Document Type and Number:
Japanese Patent JP7097440
Kind Code:
B2
Abstract:
Non-human animal genomes, non-human animal cells, and non-human animals comprising a mutated Slc30a8 locus and methods of making and using such non-human animal genomes, non-human animal cells, and non-human animals are provided. The non-human animals can have increased insulin secretory capacity.
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Inventors:
Kleiner, Sandra
Rojas, Joseev.
Gromada, Jesper
Rojas, Joseev.
Gromada, Jesper
Application Number:
JP2020525899A
Publication Date:
July 07, 2022
Filing Date:
November 09, 2018
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
C12N15/11; A01K67/027; C12N5/10; G01N33/15; G01N33/50
Foreign References:
| WO2016100857A1 |
Other References:
Nature Genetics, 2014, Vol.46, No.4, pp.357-364
PNAS, 2018, Vol.115, No.32, pp.E7642-E7649
J of Diabetes Research, 2013, Vol.2013, Article ID 906590, pp.1-12
PNAS, 2018, Vol.115, No.32, pp.E7642-E7649
J of Diabetes Research, 2013, Vol.2013, Article ID 906590, pp.1-12
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Morishita Natsuki
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