Title:
薬理学的及び毒性学的研究のための非ヒトトランスジェニック動物
Document Type and Number:
Japanese Patent JP2004533826
Kind Code:
A
Abstract:
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
Inventors:
Daley, John, Michael
Application Number:
JP2002582235A
Publication Date:
November 11, 2004
Filing Date:
April 18, 2002
Export Citation:
Assignee:
Gene Stream Proprietary Limited
International Classes:
A01K67/027; C07K14/47; C07K14/765; C12N15/09; C12N15/12; C12N15/85; G01N33/15; G01N33/68; (IPC1-7): A01K67/027; G01N33/15; G01N33/68
Attorney, Agent or Firm:
Ken Takahashi