抗腫瘍作用を有する新規ＲＮＡ配列

Title:

抗腫瘍作用を有する新規ＲＮＡ配列

Document Type and Number:

Japanese Patent JP6560190

Kind Code:

B2

Abstract:

Provided is a novel useful microRNA having improved anti-tumour activity, obtained by introducing a variation in a microRNA which is present in-vivo and which exhibits an anti-tumour effect. This microRNA containing a base sequence (SEQ ID NO: 1) obtained by varying a predetermined region of the base sequence of miR-29b is able to exhibit a particularly outstanding anti-tumour effect.

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Inventors:

Hirofumi Yamamoto
Masaki Mori
Yuichiro Toki

Application Number:

JP2016506529A

Publication Date:

August 14, 2019

Filing Date:

March 04, 2015

Export Citation:

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Assignee:

Hirofumi Yamamoto
Masaki Mori

International Classes:

C12N15/113; A61K31/7105; A61K48/00; A61P1/00; A61P35/00

Domestic Patent References:

JP2006509838A

Foreign References:

WO2013109604A1

Other References:

PLOS ONE,2013年,vol.8, no.10,e75034
Hepatology,2011年,vol.54, no.5,p.1729-40

Attorney, Agent or Firm:

Junya Tanaka
Mizuya Kamiya

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