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Title:
NOVEL ARYLAZO COMPOUND
Document Type and Number:
Japanese Patent JPS5618949
Kind Code:
A
Abstract:
The invention relates to new arylazo compounds of the general formula wherein R1 and R2 independently of each other represent hydrogen or C1-3-alkyl, R3 represent hydrogen, halogen, C1-3-alkyl, C1-3-alkoxy, carboxy, C1-3-alkoxycarbonyl, C1-3-alkylcarbonyl or a group X-NH-SO2-, wherein X represents a heterocyclic ring, R4 represents hydrogen, halogen or C1-3-alkyl, and n is the integer 1 or 2, the two groups being the same or different when n is 2, and lactones and salt thereof. The compounds of formula I have a high inhibiting effect on prostaglandin synthetizing and inactivating enzymes and may therefore be used as a drug and anti-fertility agent. The invention also relates to preparation of the compounds of formula I as well as pharmaceutical compositions containing the same.

Inventors:
KAARU HIYUUBAATO AGUBATSUKU
Application Number:
JP7790180A
Publication Date:
February 23, 1981
Filing Date:
June 11, 1980
Export Citation:
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Assignee:
PHARMACIA AB
International Classes:
A61K31/13; A61K31/655; A61P3/00; A61P29/00; C07C67/00; C07C241/00; C07C245/08; C07D213/76; C07D239/69; C07D263/50; C07D311/20; C07D405/12; (IPC1-7): A61K31/13; A61K31/42; A61K31/44; A61K31/505; C07C107/06; C07D213/76; C07D239/69; C07D263/50; C07D311/10; C07D405/12