Title:
NOVEL COMPOSITIONS AND METHODS
Document Type and Number:
Japanese Patent JP2018168161
Kind Code:
A
Abstract:
To provide methods for prophylaxis or treatment of disorders associated with dementia, e.g., disorders associated with mild cognition impairment and dementing illnesses.SOLUTION: A method includes administering a compound of formula I. (In the formula, X is -N(H)-, -N(CH)-, or -O-; Y is -C(=O), -C(H)(OH), or -C(H)(OR); and Ris -C(O)-Calkyl (e.g., -C(O)-Calkyl, -C(O)-Calkyl, or -C(O)-Calkyl), where the alkyl is preferably a straight chain, optionally saturated or unsaturated, and optionally substituted with one or more hydroxy or Calkoxy (e.g., ethoxy) groups; for example, Ris -C(O)-Calkyl, -C(O)-Calkyl, -C(O)-Calkyl, -C(O)-Calkyl, -C(O)-Calkyl, or -C(O)-Calkyl.)SELECTED DRAWING: None
Inventors:
MATES SHARON
ROBERT DAVIS
KIMBERLY VANOVER
LAWRENCE WENNOGLE
ROBERT DAVIS
KIMBERLY VANOVER
LAWRENCE WENNOGLE
Application Number:
JP2018107717A
Publication Date:
November 01, 2018
Filing Date:
June 05, 2018
Export Citation:
Assignee:
INTRA CELLULAR THERAPIES INC
International Classes:
A61K31/4985; A61K31/13; A61K31/27; A61K31/445; A61K31/473; A61K31/5383; A61K31/55; A61K45/00; A61P25/00; A61P25/14; A61P25/16; A61P25/24; A61P25/28; A61P31/00; A61P43/00
Domestic Patent References:
| JP2011523949A | 2011-08-25 |
Foreign References:
| US20040220178A1 | 2004-11-04 | |||
| US6552017B1 | 2003-04-22 | |||
| WO2000077002A1 | 2000-12-21 | |||
| WO2011133224A1 | 2011-10-27 |
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精神経誌, vol. 110, no. 7, JPN6020002812, 2008, pages 577 - 584, ISSN: 0004202114
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日薬理誌, vol. 128, JPN6019023928, 2006, JP, pages 173 - 176, ISSN: 0004202116
MEBIO, vol. 28, no. 5, JPN6019023929, 2011, JP, pages 104 - 111, ISSN: 0004202117
Attorney, Agent or Firm:
Michiko Matsutani
Yasushi Ochiai
Yasushi Ochiai